"Psycho Killer" is a song written by David ByrneChris Frantz and Tina Weymouth and first played by their band The Artistic in 1974, and as New Wave band Talking Heads in 1975,with a later version recorded for their 1977 album Talking Heads: 77. The band's "signature debut hit" features lyrics which seem to represent the thoughts of a serial killer. Originally written and performed as a ballad, "Psycho Killer" became what Allmusic calls a "deceptively funky New Wave/No Wave song ... [with] an insistent rhythm, and one of the most memorable, driving basslines in rock & roll."

"Psycho Killer" was the only song from the album to appear on the Billboard Pop Singles chart, peaking at number 92. It placed 32nd on the Triple J Hottest 100 in 1989, and peaked at #11 on the Dutch singles chart in 1977.

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